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Anti-Human CD107a (LAMP-1) FITC 25 tests

ArtNr 19111-50-25
Hersteller BioGems
Menge 25 tests
Kategorie
Typ Antibody
Format FITC
Applikationen FC
Clon H4A3
Specific against Human
Host Mouse
Isotype IgG1 kappa
Konjugat/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Description
The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.
Research Interest
Innate Immunity
Preperation
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation
Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References

Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., & August, J. T. (1988). Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens. Journal of Biological Chemistry, 263(18), 8754-8758.

Grützkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., & Henz, B. M. (2004). LAMP-1 and LAMP-2, but not LAMP-3, are reliable markers for activation-induced secretion of human mast cells. Cytometry Part A, 61(1), 62-68.

Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... & Coninck, W. D. (1998). Expression of LAMP-1 and LAMP-2 and their interactions with galectin-3 in human tumor cells. International journal of cancer, 75(1), 105-111.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 tests
Lieferbar: In stock
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