ArtNr |
OPPA00540 |
Hersteller |
AVIVA Systems Biology
|
Menge |
2ug |
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized from a concentrated (1mg/ml) solution in water containing 10mM Sodium phosphate buffer pH=6.5. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
Specific against |
other |
Host |
E.coli |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250, Hematopoietic growth factor KL, Steel factor, SCF Mouse, Recombinant Mouse Stem Cell Factor |
Similar products |
mSCF |
Lieferbar |
|
Gene symbol |
mSCF |
Protein name |
Kit ligand |
Molecular weight |
18 kDa |
Product format |
Lyophilized from a concentrated solution in water containing 0.02% NaHCO3 Physical Appearance: Sterile filtered white freeze-dried powder |
Gene id |
17311 |
Reconstitution and storage |
It is recommended to reconstitute the lyophilized Stem Cell Factor in sterile 18M-omega-cm H2O not less than 100 ug/mL, which can be further diluted to other aqueous solutions. Lyophilized KIT ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution SCF should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Description of target |
Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid). |
Purification |
Purified by proprietary chromatographic techniques. |
Biological activity |
The ED50 as determined by the dose-dependent stimulation of Human TF-1 cell line is <10 ng/ml, corresponding to a Specific Activity of 1x105 IU/mg. |
Purity |
Greater than 98.0% as determined by (a) Analysis by SEC-HPLC (b) Analysis by SDS-PAGE |
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