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LAMTOR3 Recombinant Protein

ArtNr OPCD05133
Hersteller AVIVA Systems Biology
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Applikationen WB, SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Unconjugated; HIS
Purity > 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias late endosomal/lysosomal adaptor and MAPK and MTOR activator 3;MAP2K1IP1;MAPBP;MAPK scaffold protein 1;MAPKSP1;MEK binding partner 1;MEK-binding partner 1;mitogen-activated protein kinase kinase 1 interacting protein 1;Mitogen-activated protein kinase kinase 1-interacting protein 1;mitogen-activated protein kinase scaffold protein 1;MP1;PRO0633;ragulator complex protein LAMTOR3;Ragulator3.
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Manufacturer - Type
Protein
Manufacturer - Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Manufacturer - Category
Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag
N-terminal His Tag
Molecular Weight
17.32kDa
Gene symbol
LAMTOR3
Gene Fullname
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Protein size
Recombinant
Product format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage
2°C to 8°C|-80°C
Description of target
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Nucleotide accession_num
NM_001243736.1
Protein accession_num
NP_001230665.1
Protein name
Ragulator complex protein LAMTOR3
Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration
200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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