CBFA2T3 Antibody - middle region (OASG02597)

Wet Ice

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16; 21)(q24; q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5' -region of the runt-related transcription factor 1 gene fused to the 3' -region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.