LACC1 Antibody (OAGA06307)

laccase domain-containing protein 1

144811

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet' s disease, leprosy, ulcerative colitis, early-onset Crohn' s disease, and systemic juvenile idiopathic arthritis.

Polyclonal

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