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Anti-BCAR3 Antibody (Phospho-T130) (OAAI00367)

Anti-BCAR3 Antibody (Phospho-T130) (OAAI00367)

ArtNr	OAAI00367
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NSP2, SH2D3B
Similar products	NSP2, SH2D3B
Lieferbar
Gene symbol	BCAR3
Molecular weight	93 kDa
Gene id	8412
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
Description of target	Breast cancer anti-estrogen resistance 3 (BCAR3) is a also known as AND-34/BCAR3/NSP2 (BCAR3). Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. BCAR3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent prolifeRation in Human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48
Purification	The rabbit IgG is purified by site-directed Eptiope Affinity Purification.
Clonality	Polyclonal
Immunogen	A synthetic peptide surrounding of - DRTPE- of Human BCAR3 protein with a single phosphorylation site. This sequence is identical to Human, Rat, Mouse, canis and bovine.
Drywet	Wet Ice

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Menge: 100 ug

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