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IDH1 antibody - N-terminal region (OAAB04488)

IDH1 antibody - N-terminal region (OAAB04488)

ArtNr	OAAB04488
Hersteller	AVIVA Systems Biology
Menge	400ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Cell Biology Cell Status Necrosis Myelofibrosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma By Organ Brain Cancer
Typ	Antibody Polyclonal
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH, IDP , PICD, name: IDH1
Similar products	IDH1
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Gene symbol	IDH1
Protein name	Isocitrate dehydrogenase [NADP] cytoplasmic
Molecular weight	46659 Da
Product format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Gene id	3417
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Homology	Cow; Human; Mouse; Rat
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality	Polyclonal
Immunogen	This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human IDH1.
Drywet	Wet Ice

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