ArtNr |
ARP39277_P050 |
Hersteller |
AVIVA Systems Biology
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat, Porcine, Rabbit, Fish, Guinea Pig, Bovine, Canine, Equine |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FLJ40871, KIAA1129, MGC44594, PHA2D |
Similar products |
KLHL3 |
Lieferbar |
|
Gene symbol |
KLHL3 |
Protein name |
Kelch-like protein 3 |
Protein size |
587 |
Molecular weight |
65kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
26249 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
WNK4. KLHL12. KLHL3. KEAP1. MORF4L2. CUL3. UBC. C6orf165. WNK3. WNK2. WNK1. RBX1. SLC12A3. ELAVL1. SYNCRIP. SYT2. OPRD1. GNAO1. GNAI1. |
Description of target |
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q. |
Homology |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human KLHL3 |
Drywet |
Wet Ice |
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