ArtNr |
STJ114341-100 |
Hersteller |
St John's Laboratory
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Nephrin antibody</br>Anti-Renal Glomerulus-Specific Cell Adhesion Receptor antibody</br>Anti-NPHS1 NPHN antibody |
Similar products |
Anti-Nephrin antibodyAnti-Renal Glomerulus-Specific Cell Adhesion Receptor antibodyAnti-NPHS1 NPHN antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O60500 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 1100 to the C-terminus of human NPHS1 (NP_004637. 1). |
Short Description |
Rabbit polyclonal against NPHS1 |
Tissue specificity |
Specifically expressed in podocytes of kidney glomeruli. |
Cellular localization |
Cell MembraneSingle-Pass Type I Membrane ProteinPredominantly Located At Podocyte Slit Diaphragm Between Podocyte Foot ProcessesAlso Associated With Podocyte Apical Plasma Membrane |
Molecular weight |
Calculated: 130kDa/134kDa. Observed: 185kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Nephrin antibodyAnti-Renal Glomerulus-Specific Cell Adhesion Receptor antibodyAnti-NPHS1 NPHN antibody |
Protein name |
NephrinRenal Glomerulus-Specific Cell Adhesion Receptor |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.