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Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AS113) (Omicron Specific) Europäischer Partner

ArtNr SPD-M415-100ug
Hersteller ACROBiosystems
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Powder
Specific against Human
Host HEK293
Isotype IgG1
Konjugat/Tag Unconjugated
Purity 95%
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Lieferbar
Manufacturers Category
Antibody / Recombinant Antibodies
Description
Anti-SARS-CoV-2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with omicron Spike RBD. The antibody is specific against the Omicron (B.1.1.529/BA.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and other viral lineages.
Molecule
Spike RBD
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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