Background |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Manufacturers Research Area |
Epigenetics & Nuclear Signaling, Transcription Factors, Cancer, Tumor biomarkers, Signal Transduction, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Immunology & Inflammation, T Cell Receptor Signaling Pathway, Neuroscience, Cell Type Marker, Neuron marker, Protein phosphorylation |