ArtNr |
RD85851A-20uL |
Hersteller |
Reddot Biotech
|
Menge |
20 uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, ELISA, IHC-P |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ATP dependent DNA helicase VIII,ATP-dependent DNA helicase VIII,G3BP,G3BP stress granule assembly factor 1,G3BP-1,G3bp1,G3BP1,GAP binding protein,GAP SH3 domain binding protein 1,GAP SH3 domain-binding protein 1,GTPase activating protein (SH3 domain) binding protein 1,hDH VIII,Human DNA helicase VIII,MGC111040,Ras GTPase activating protein binding protein 1,Ras GTPase activating protein SH3 domain binding protein,Ras GTPase-activating protein-binding protein 1,RasGAP associated endoribonuclease G3BP |
Lieferbar |
|
Background |
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. |
Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Clonality |
Polyclonal |
Concentration |
1mg/mL |
Dilution |
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000 |
Immunogen |
Synthesized peptide derived from human G3BP1 around the phosphorylation site of Ser232 |
Purification_Method |
Affinity purification |
Storage |
Store at -20℃. Avoid repeated freeze / thaw cycles. |
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