Alias |
ARA,FKH L7,FKHL 7,FKHL7,Forkhead (Drosophila) like 7,Forkhead box C1,Forkhead box protein C1,Forkhead drosophila homolog like 7,Forkhead like 7,Forkhead related activator 3,Forkhead related protein FKHL7,Forkhead related transcription factor 3,Forkhead-related protein FKHL7,Forkhead-related transcription factor 3,FOX C1,FOXC 1,Foxc1,FOXC1,FREAC 3,FREAC-3,FREAC3,IGDA,IHG 1,IHG1,IRID 1,IRID1,Iridogoniodysgenesis type 1,Myeloid factor delta |
Background |
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. |