Alias |
beta1 integrin,CD29,Fibronectin receptor subunit beta,FNRB,Glycoprotein IIa,GP IIa,GPIIA,Integrin beta-1,Integrin subunit beta 1,integrin VLA-4 beta subunit,Integrin,beta 1 (fibronectin receptor,antigen CD29 includes MDF2,MSK12),ITB1,ITGB1,MDF2,MSK12,OTTHUMP00000019420,Very late activation protein,beta polypeptide,VLA BETA,VLA-4 subunit beta,VLA-BETA,VLAB,VLAbeta |
Background |
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. |