Alias |
c FLIP,c FLIPL,c FLIPR,c FLIPS,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,CASH,CASP8 and FADD like apoptosis regulator,CASP8 and FADD-like apoptosis regulator subunit p12,CASP8AP1,Caspase homolog,Caspase like apoptosis regulatory protein,Caspase related inducer of apoptosis,Caspase-eight-related protein,Caspase-like apoptosis regulatory protein,Casper,Cellular FLICE-like inhibitory protein,CFLA,Cflar,CFLAR,CLARP,FADD like anti apoptotic molecule,FADD-like antiapoptotic molecule 1,FLAME,FLAME-1,FLAME1,FLIP,I FLICE,I-FLICE,Inhibitor of FLICE,MACH-related inducer of toxicity,MRIT,OTTHUMP00000163715,OTTHUMP00000206475,OTTHUMP00000206476,OTTHUMP00000206478,OTTHUMP00000206479,OTTHUMP00000206480,OTTHUMP00000206482,OTTHUMP00000207360,Usurpin,Usurpin beta |
Background |
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. |