Alias |
EDG6,Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6,Endothelial differentiation G protein coupled receptor 6,Endothelial differentiation G-protein coupled receptor 6,Endothelial differentiation gene 6,LPC1,Lysophospholipid receptor C1,MGC129298,Putative G protein coupled receptor,S1P receptor 4,S1P receptor Edg-6,S1P receptor Edg6,S1P4,S1PR4,SLP4,Sphingosine 1 phosphate receptor 4,Sphingosine 1 phosphate receptor Edg6,Sphingosine 1-phosphate receptor 4,Sphingosine 1-phosphate receptor Edg-6 |
Background |
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. |