Alias |
B cell chronic lymphocytic leukemia tumor suppressor Leu5,B-cell chronic lymphocytic leukemia tumor suppressor Leu5,CAR,DLEU5,E3 ubiquitin-protein ligase TRIM13,HGNC:9976,LEU5,Leukemia associated protein 5,Leukemia-associated protein 5,Putative tumor suppressor RFP2,Ret finger protein 2,RING finger protein 77,RNF77,TRI13,Trim13,Tripartite motif protein 13,Tripartite motif-containing protein 13 |
Background |
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene. |