Alias |
A1M,Alpha 1 microglobulin/bikunin precursor,Alpha 1 microglycoprotein,Alpha-1 microglycoprotein,Alpha-1-microglobulin,AMBP,Bikunin,Complex-forming glycoprotein heterogeneous in charge,EDC1,Growth inhibiting protein 19,HCP,HI-30,HI30,IATIL,ITI,ITI-LC,ITIL,Microglobulin (alpha 1),Protein AMBP,Protein HC,Trypstatin,Uristatin,Uronic-acid-rich protein,UTI |
Background |
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. |