ArtNr |
RD71629A-200uL |
Hersteller |
Reddot Biotech
|
Menge |
200 uL |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ODPA,PDH,PDHA,PDHA1,PDHCE1A,PDHE1 A type I,PDHE1-A type I,PHE1A,Pyruvate Dehydrogenase (lipoamide) alpha 1,Pyruvate dehydrogenase complex,E1 alpha polypeptide 1,Pyruvate Dehydrogenase E1 alpha,Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial |
Lieferbar |
|
Background |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Clonality |
Polyclonal |
Concentration |
1mg/mL |
Dilution |
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000 |
Immunogen |
Synthesized peptide derived from the C-terminal region of human PDHA1 |
Purification_Method |
Affinity purification |
Storage |
Store at -20℃. Avoid repeated freeze / thaw cycles. |
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