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Rabbit anti-DcR3 Polyclonal Antibody

ArtNr RD71052A-200uL
Hersteller Reddot Biotech
Menge 200 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, ELISA, IHC-P
Specific against Human
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DcR3,Decoy receptor 3,Decoy receptor for Fas ligand,DJ583P15.1.1,M68,M68E,OTTHUMP00000031583,TNF6B,TNFRSF6B,TR6,Tumor necrosis factor receptor superfamily member 6B,Tumor necrosis factor receptor superfamily member 6b decoy,UNQ186/PRO212
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Background
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.TNFRSF6B (TNF Receptor Superfamily Member 6b) is a Protein Coding gene. Diseases associated with TNFRSF6B include Bladder Urothelial Carcinoma and Oral Cavity Cancer. Among its related pathways are Apoptosis and Autophagy and Innate Immune System. GO annotations related to this gene include receptor activity. An important paralog of this gene is TNFRSF11B.
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Clonality
Polyclonal
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen
Synthesized peptide derived from the C-terminal region of human DcR3
Purification_Method
Affinity purification
Storage
Store at -20℃. Avoid repeated freeze / thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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