Anti-Integrin beta 4 Mouse mAb

Uncategorized

Store at -20°C. Avoid freeze/thaw cycles.

Anti-Integrin beta 4 Mouse mAb

PBS, Glycerol, BSA

Recombinant Monoclonal

Integrin β4 belongs to Integrins family, which contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrin β4 pairs with integrin α6 on the cell surface membrane to form the integrin α6β4 heterodimer, an important laminin receptor that is essential for hemidesmosome formation and the support of stable adhesions between basal epithelial cells and the basement membrane. Integrin β4 is an important component in several growth factor induced signaling pathways that are involved in tumorigenesis and invasive cell growth.