Anti-CD68 Mouse mAb

Uncategorized

Store at -20°C. Avoid freeze/thaw cycles.

Anti-CD68 Mouse mAb

PBS, Glycerol, BSA

Recombinant Monoclonal

CD68 is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages. CD68 is a transmembrane glycoprotein, heavily glycosylated in its extracellular domain. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.