ArtNr |
PRS-XPS-2002-0.1mL |
Hersteller |
ProSci
|
Menge |
0.1 mL |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human, Rat, Bovine, Ovine |
Host |
Sheep |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Neuroscience |
Immunogen |
DBH polyclonal antibody was raised against a synthetic peptide from the N-terminal region of human DBH, conjugated to keyhole limpet hemocyanin. |
Applications |
Applications include Dot Blots (DB) and Western Blots (WB). Sheep anti-DBH recognizes DBH in bovine, human, monkey and rat tissues. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB. |
Specificity |
Dopamine b-Hydroxylase, NT antibody is specific immunolabeling of the ~75k DBH protein in Western blots of human adrenal medulla. |
Predicted Molecular Weight |
75 |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Storage Conditions |
For long term storage –80˚ C is recommended, but shorter term storage at –20˚ C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
DBH |
Accession # |
P09172 |
Protein Gi # |
158517849 |
Ncbi Gene Id # |
1621 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
DBH |
Ncbi Official Full Name |
dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P09172 |
Background |
Dopamine beta-hydroxylase (DBH) catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. The expression of DBH is elevated during stress. |
Background References 1 |
Sabban, E.L., Kvetnansky, R. "Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional events, " Trends Neurosci. 24 (2001) 91 - 98. |
Background References 2 |
Nagatsu, I, Kobayashi, K, Fujii, T, Komori, K, Sekiguchi, K, Titani, K, Fujita, K, and Nagatsu, T. "Antibodies raised against different oligopeptide segments of human dopamine-β -hydroxylase, " Neuroscience Letters, 120 (1990) 141 - 145. |
1st Image Caption |
Dopamine beta-Hydroxylase, NT Antibody |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.