« Zurück
Home /
KIRREL3 Antibody

KIRREL3 Antibody

ArtNr	PRS-7973-0.02mg
Hersteller	ProSci
Menge	0.02 mg
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Kin of irregular chiasm-like protein 3, Kin of IRRE-like protein 3, MRD4, KIRRE, NEPH2, PRO4502, Nephrin-like protein 2
Lieferbar
Shipping	blue ice or RT
By Research Area	Neuroscience, Stem Cell
Immunogen	KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3. The immunogen is located within amino acids 20 - 70 of KIRREL3.
Applications	KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ g/ml. Antibody can also be used for immunohistochemistry starting at 5 μ g/mL. For immunofluorescence start at 20 μ g/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificity	KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
Positive Control 1	Cat. No. 1405 - Mouse Kidney Tissue Lysate
Predicted Molecular Weight	Predicted: 64, 84 kDa Observed: 60 kDa
Purification	KIRREL3 antibody is affinity chromatography purified via peptide column.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	KIRREL3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/mL
Storage Conditions	KIRREL3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Related Products	Cat. No. 7973P – KIRREL3 Peptide
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	KIRREL3
Accession #	NP_115920
Protein Gi #	26006461
Ncbi Gene Id #	84623
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	KIRREL3
Ncbi Official Full Name	kin of IRRE like 3 (Drosophila)
Ncbi Organism	homo sapiens
Swissprot #	Q8IZU9
Background	KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).
Background References 1	Sellin L, Huber TB, Gerke P, et al. NEPH1 defines a novel family of podocin interacting proteins. FASEB J. 2003; 17:115-7.
Background References 2	Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, et al. A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis. Hum. Mol. Genet. 2010; 19:2347-59.
Background References 3	Nishida K, Nakayama K, Yoshimura S, et al. Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol. Cell Neurosci. 2011; 46:662-70.
Background References 4	Mizuhara E, Minaki Y, Nakatani T, et al. Purkinje cells originate from cerebellar ventricular zone progenitors positive for Neph3 and E-cadherin. Dev. Biol. 2010; 338:202-14.
1st Image Caption	Western blot analysis of KIRREL3 in mouse kidney tissue lysate with KIRREL3 antibody at (A) 1 and (B) 2 μ g/ml.
2nd Image Caption	Immunohistochemistry of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 5 μ g/ml.
3rd Image Caption	Immunofluorescence of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 20 μ g/ml.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkdatenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 0.02 mg

lieferbar

Lieferung vsl. bis 04.10.2024

Express-Lieferung: 10 Tage sparen

Vergleichen

Auf den Wunschzettel

Weiterempfehlen per Mail