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Tip60 (phospho Ser90) Antibody

Tip60 (phospho Ser90) Antibody

ArtNr	PRS-79-924-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Antibodies Immunohistochemistry Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HTATIP, TI60, Tat-interactive protein-60
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Shipping	blue ice or RT
By Research Area	Phospho-Specific
Immunogen	Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p)-P-E) derived from Human Tip60.
Specificity	The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.
Predicted Molecular Weight	58 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	Phospho-Specific
Ncbi Official Symbol	KAT5
Accession #	NP_006379.2
Protein Gi #	36287069
Ncbi Gene Id #	10524
Ncbi Official Symbol	KAT5
Ncbi Official Full Name	K(lysine) acetyltransferase 5
Ncbi Organism	Homo sapiens
Swissprot #	Q92993
Background	The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Background References 1	Kamine J., Virology 216:357-366(1996).
Background References 2	Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).
Background References 3	Legube G., Gene 310:161-168(2003).
2nd Image Caption	Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody (left) or the same antibody preincubated with blocking peptide (right).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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