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iNOS (phospho Tyr151) Antibody

iNOS (phospho Tyr151) Antibody

ArtNr	PRS-79-877-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry Enzymes Other Fatty Acid Enzymes Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HEP-NOS, NOS2, inducible
Lieferbar
Shipping	blue ice or RT
By Research Area	Phospho-Specific
Immunogen	iNOS (phospho Tyr151) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y (p)-G-S) derived from Human iNOS .
Specificity	The antibody detects endogenous levels of Inos only when phosphorylated at tyrosine 151.
Predicted Molecular Weight	131 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	Phospho-Specific
Ncbi Official Symbol	NOS2
Accession #	NP_000616.3
Protein Gi #	1352513
Ncbi Gene Id #	4843
Ncbi Official Symbol	NOS2
Ncbi Official Full Name	nitric oxide synthase 2, inducible
Ncbi Organism	Homo sapiens
Swissprot #	P35228
Background	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Background References 1	Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).
Background References 2	Sherman P.A., Biochemistry 32:11600-11605(1993).
Background References 3	Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993).
2nd Image Caption	Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Inos (Phospho-Tyr151) antibody (left) or the same antibody preincubated with blocking peptide (right).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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Lieferung vsl. bis 06.09.2024

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