ArtNr |
PRS-79-682-0.1mg |
Hersteller |
ProSci
|
Menge |
0.1 mg |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NEP, SFE, CD10, CALLA, NEP, MME, MGC126681 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Stem Cell |
Immunogen |
CD10 antibody was raised against a peptide sequence around aa.6~10 (S-Q-M-D-I) derived from Human CD10. |
Applications |
Western Blot: 1:500 |
Specificity |
This antibody detects endogenous level of total CD10 protein. |
Predicted Molecular Weight |
100 kDa |
Purification |
Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration |
1 mg/mL |
Storage Conditions |
Store antibody at -20˚ C for up to one year. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MME |
Accession # |
NP_000893.2 |
Protein Gi # |
116256329 |
Ncbi Gene Id # |
4311 |
Ncbi Official Symbol |
MME |
Ncbi Official Full Name |
membrane metallo-endopeptidase |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P08473 |
Background |
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
Background References 1 |
Yandle T. G., Brennan S. O., Espiner E. A., Nicholls M. G., Richards A. M. Peptides 10:891-894 (1989) Rice G. I., Thomas D. A., Grant P. J., Turner A. J., Hooper N. M. Biochem. J. 383:45-51 (2004) Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G. J. Biol. Chem. 285:39819-39827 (2010) |
1st Image Caption |
Western blot analysis of extract from Rat kidney tissue using CD10 Antibody. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.