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Myc (phospho Thr58) Antibody

Myc (phospho Thr58) Antibody

ArtNr	PRS-79-117-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MRTL, MYCC, c-Myc, bHLHe39, BBC6, BCL2L8, c-myc
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Shipping	blue ice or RT
By Research Area	Phospho-Specific, Apoptosis, Cancer, Cell Cycle
Immunogen	Myc (Phospho-Thr58) antibody was raised against a peptide sequence around phosphorylation site of threonine 58 (L-P-T (p) -P-P) derived from Human Myc.
Applications	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity	This antibody detects endogenous level of Myc only when phosphorylated at threonine 58.
Predicted Molecular Weight	60 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality	Polyclonal
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	Phospho-Specific
Ncbi Official Symbol	MYC
Accession #	NP_002458.2
Protein Gi #	71774083
Ncbi Gene Id #	4609
Ncbi Official Symbol	MYC
Ncbi Official Full Name	v-myc avian myelocytomatosis viral oncogene homolog
Ncbi Organism	Homo sapiens
Swissprot #	P01106
Background	Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
Background References 1	Jin Z, et al. (2004) J Biol Chem. 279 (38): 40209-40219. Welcker M, et al. (2004) Proc Natl Acad Sci U S A. 101 (24): 9085-9090. Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.
1st Image Caption	Western blot analysis of lysed extracts from HeLa cells using Myc (Phospho-Thr58).
2nd Image Caption	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc (Phospho-Thr58).

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Menge: 0.1 mg

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