ArtNr |
PRS-79-117-0.1mg |
Hersteller |
ProSci
|
Menge |
0.1 mg |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
MRTL, MYCC, c-Myc, bHLHe39, BBC6, BCL2L8, c-myc |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Phospho-Specific, Apoptosis, Cancer, Cell Cycle |
Immunogen |
Myc (Phospho-Thr58) antibody was raised against a peptide sequence around phosphorylation site of threonine 58 (L-P-T (p) -P-P) derived from Human Myc. |
Applications |
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100 |
Specificity |
This antibody detects endogenous level of Myc only when phosphorylated at threonine 58. |
Predicted Molecular Weight |
60 kDa |
Purification |
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration |
1 mg/mL |
Storage Conditions |
Store antibody at -20˚ C for up to one year. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
Phospho-Specific |
Ncbi Official Symbol |
MYC |
Accession # |
NP_002458.2 |
Protein Gi # |
71774083 |
Ncbi Gene Id # |
4609 |
Ncbi Official Symbol |
MYC |
Ncbi Official Full Name |
v-myc avian myelocytomatosis viral oncogene homolog |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P01106 |
Background |
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. |
Background References 1 |
Jin Z, et al. (2004) J Biol Chem. 279 (38): 40209-40219. Welcker M, et al. (2004) Proc Natl Acad Sci U S A. 101 (24): 9085-9090. Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. |
1st Image Caption |
Western blot analysis of lysed extracts from HeLa cells using Myc (Phospho-Thr58). |
2nd Image Caption |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc (Phospho-Thr58). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.