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CD3 Antibody [G4.18] (FITC)

CD3 Antibody [G4.18] (FITC)

ArtNr	PRS-76-237-0.05mg
Hersteller	ProSci
Menge	0.05 mg
Kategorie	Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC
Specific against	Rat
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cd3d, Cd3d
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Shipping	blue ice or RT
By Research Area	Immunology
Specificity	The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR).
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality	Monoclonal
Clone	G4.18
Isotype	Mouse IgG3, kappa
Conjugate	FITC
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration	batch dependent
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	Cd3d
Ncbi Gene Id #	25710
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	Cd3d
Ncbi Official Full Name	CD3 molecule, delta
Ncbi Organism	Rattus norvegicus
Swissprot #	P19377
Background	The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Background References 1	Nicolls, M. R., Aversa, G. G., Pearce, N. W., Spinelli, A., Berger, M. F., Gurley, K. E., Hall, B. M. (1993). Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody.Transplantation, 55(3), 459-468.
Background References 2	Morris, D. L., Komocsar, W. J. (1997). Immunophenotyping analysis of peripheral blood, splenic, and thymic lymphocytes in male and female rats.Journal of pharmacological and toxicological methods, 37(1), 37-46.
Background References 3	Tran, G. T., Carter, N., He, X. Y., Spicer, T. S., Plain, K. M., Nicolls, M., ... Hodgkinson, S. J. (2001). Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on Th1 cells that is augmented by IL-4.International immunology, 13(9), 1109-1120.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.05 mg

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