ArtNr |
PRS-63-413-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC-P |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170}, AK 4 {ECO:0000255|HAMAP-Rule:MF_03170}, 27410 {ECO:0000255|HAMAP-Rule:MF_03170}, 2746 {ECO:0000255|HAMAP-Rule:MF_03170}, Adenylate kinase 3-like {ECO:0000255|HAMAP-Rule:MF_03170}, GTP:AM |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Obesity, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Rat |
Immunogen |
This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human AK3. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 |
Predicted Molecular Weight |
25 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
AK4 |
Accession # |
P27144 |
Protein Gi # |
125157 |
Ncbi Gene Id # |
100507855, 205 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
AK4 |
Ncbi Official Full Name |
Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170} |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P27144 |
Background |
AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. |
Background References 1 |
Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999). |
Background References 2 |
Yoneda, T., et al., Brain Res. Mol. Brain Res. 62(2):187-195 (1998). |
Background References 3 |
Xu, G., et al., Genomics 13(3):537-542 (1992). |
Background References 4 |
Robson, E.B., et al., Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982). |
1st Image Caption |
Antibody is used in Western blot to detect AK3 in mouse kidney tissue lysate. |
2nd Image Caption |
Western blot analysis of AK3 using rabbit polyclonal AK3 Antibody (C-term H38) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3 gene (Lane 2). |
3rd Image Caption |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.