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CYP3A5 Antibody

CYP3A5 Antibody

ArtNr	PRS-63-210-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Mesothelioma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cytochrome P450 3A5, CYPIIIA5, Cytochrome P450 HLp2, Cytochrome P450-PCN3, CYP3A5
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Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Immunogen	This CYP3A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from the Central region of human CYP3A5.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	57 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CYP3A5
Accession #	P20815
Protein Gi #	117157
Ncbi Gene Id #	1577
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CYP3A5
Ncbi Official Full Name	Cytochrome P450 3A5
Ncbi Organism	Homo sapiens
Swissprot #	P20815
Background	CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
Background References 1	Zencir, S., Z. Naturforsch., C, J. Biosci. 63 (9-10), 780-784 (2008)
Background References 2	Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Background References 3	Murray, G.I., FEBS Lett. 364 (1), 79-82 (1995)
1st Image Caption	Western blot analysis of CYP3A5 Antibody in 293 cell line lysates (35ug/lane)
2nd Image Caption	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP3A5 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
3rd Image Caption	Flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.09.2024

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