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IPF Antibody

IPF Antibody

ArtNr	PRS-63-177-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot Immunofluorescence Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, PDX1, IPF1, STF1
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Shipping	blue ice or RT
By Research Area	Cancer, Cell Cycle, Obesity, Signal Transduction
Immunogen	This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.
Applications	For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50
Predicted Molecular Weight	31 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PDX1
Accession #	P52945
Protein Gi #	1708540
Ncbi Gene Id #	3651
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PDX1
Ncbi Official Full Name	Pancreas/duodenum homeobox protein 1
Ncbi Organism	Homo sapiens
Swissprot #	P52945
Background	IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Background References 1	Ma, J., Carcinogenesis 29 (7), 1327-1333 (2008)
Background References 2	Watada, H., Biochem. Biophys. Res. Commun. 229 (3), 746-751 (1996)
1st Image Caption	Western blot analysis in U-937 cell line lysates (35ug/lane).
2nd Image Caption	Fluorescent confocal image of U251 cell stained with IPF Antibody .U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with IPF primary antibody (1:25). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400).Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.09.2024

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