ArtNr |
PRS-62-149-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody |
Format |
Liquid |
Applikationen |
WB, IHC-P |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Melanoma-associated antigen 10, Cancer/testis antigen 110, CT110, MAGE-10 antigen, MAGEA10, MAGE10 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer |
Immunogen |
This MAGEA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human MAGEA10. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 |
Predicted Molecular Weight |
41 kDa |
Purification |
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MAGEA10 |
Accession # |
P43363 |
Protein Gi # |
317373386 |
Ncbi Gene Id # |
4109 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
MAGEA10 |
Ncbi Official Full Name |
Melanoma-associated antigen 10 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P43363 |
Background |
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. |
Background References 1 |
Rogner, U.C., et al., Genomics 29(3):725-731 (1995). |
Background References 2 |
De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994). |
1st Image Caption |
Antibody is used in Western blot to detect MAGEA10 in HL60 lysate. |
2nd Image Caption |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma. |
3rd Image Caption |
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MAGEA10 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.