ArtNr |
PRS-61-019-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, Tfap2a, Ap2tf, Tcfap2a |
Lieferbar |
|
Shipping |
blue ice or RT |
Homology |
Predicted species reactivity based on immunogen sequence: Bovine, Rat |
Immunogen |
This mouse Tfap2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the Central region of mouse Tfap2a. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
48 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
Tfap2a |
Accession # |
P34056 |
Ncbi Gene Id # |
21418 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
Tfap2a |
Ncbi Official Full Name |
Transcription factor AP-2-alpha |
Ncbi Organism |
Mus musculus |
Swissprot # |
P34056 |
Background |
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. |
Background References 1 |
Moser M., et al.Nucleic Acids Res. 21:4844-4844(1993). |
Background References 2 |
Meier P., et al.Dev. Biol. 169:1-14(1995). |
Background References 3 |
Carninci P., et al.Science 309:1559-1563(2005). |
Background References 4 |
Mitchell P.J., et al.Genes Dev. 5:105-119(1991). |
1st Image Caption |
Western blot analysis of lysate from mouse thymus tissue lysate, using Mouse Tfap2a Antibody at 1:1000 at each lane. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.