ArtNr |
PRS-60-561-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Transcription factor EC, TFE-C, Class E basic helix-loop-helix protein 34, bHLHe34, Transcription factor EC-like, hTFEC-L, TFEC, BHLHE34, TCFEC, TFECL |
Lieferbar |
|
Shipping |
blue ice or RT |
Homology |
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat |
Immunogen |
This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
39 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
TFEC |
Accession # |
O14948 |
Ncbi Gene Id # |
22797 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
TFEC |
Ncbi Official Full Name |
Transcription factor EC |
Ncbi Organism |
Homo sapiens |
Swissprot # |
O14948 |
Background |
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form. |
Background References 1 |
Mansky, K.C., et al. J. Leukoc. Biol. 71(2):304-310(2002) |
Background References 2 |
Chung, M.C., et al. Biochemistry 40(30):8887-8897(2001) |
Background References 3 |
Steingrimsson, E., et al. Development 125(23):4607-4616(1998) |
Background References 4 |
Yasumoto, K., et al. Biochim. Biophys. Acta 1353(1):23-31(1997) |
1st Image Caption |
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.