ArtNr |
PRS-60-169-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein, PDLIM3, ALP |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Signal Transduction |
Immunogen |
This PDLIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-355 amino acids from the C-terminal region of human PDLIM3. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
39 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
PDLIM3 |
Accession # |
Q53GG5 |
Protein Gi # |
74740479 |
Ncbi Gene Id # |
27295 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
PDLIM3 |
Ncbi Official Full Name |
PDZ and LIM domain protein 3 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q53GG5 |
Background |
The protein encoded by this gene contains a PDZ domain anda LIM domain, indicating that it may be involved in cytoskeletalassembly. In support of this, the encoded protein has been shown tobind the spectrin-like repeats of alpha-actinin-2 and to colocalizewith alpha-actinin-2 at the Z lines of skeletal muscle. This geneis found near a region of chromosome 4 that has been implicated infacioscapulohumeral muscular dystrophy, but this gene does notappear to be involved in the disease. Two transcript variantsencoding different isoforms have been found for this gene. |
Background References 1 |
Hershberger, R.E., et al. Clin Transl Sci 1(1):21-26(2008) |
Background References 2 |
Keira, Y., et al. Neurosci. Res. 57(4):513-521(2007) |
Background References 3 |
Arola, A.M., et al. Mol. Genet. Metab. 90(4):435-440(2007) |
Background References 4 |
Klaavuniemi, T., et al. J. Biol. Chem. 279(25):26402-26410(2004) |
1st Image Caption |
Western blot analysis in HL-60 cell line lysates (35ug/lane). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.