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LAX1 Antibody

LAX1 Antibody

ArtNr	PRS-60-025-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX
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Shipping	blue ice or RT
By Research Area	Immunology, Signal Transduction
Immunogen	This LAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human LAX1.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	44 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	LAX1
Accession #	Q8IWV1
Protein Gi #	74728197
Ncbi Gene Id #	54900
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	LAX1
Ncbi Official Full Name	Lymphocyte transmembrane adapter 1
Ncbi Organism	Homo sapiens
Swissprot #	Q8IWV1
Background	LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Background References 1	Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
Background References 2	Shapiro, M.J., et al. J. Immunol. 181(10):7055-7061(2008)
Background References 3	Zhu, M., et al. J. Immunol. 174(9):5612-5619(2005)
Background References 4	Zhu, M., et al. J. Biol. Chem. 277(48):46151-46158(2002)
1st Image Caption	Western blot analysis in K562 cell line lysates (35ug/lane).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.09.2024

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