ArtNr |
PRS-59-814-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Cell Cycle, Cell Cycle, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Mouse |
Immunogen |
This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
37 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
OSTM1 |
Accession # |
Q86WC4 |
Protein Gi # |
51316434 |
Ncbi Gene Id # |
28962 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
OSTM1 |
Ncbi Official Full Name |
Osteopetrosis-associated transmembrane protein 1 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q86WC4 |
Background |
This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis. |
Background References 1 |
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009) |
Background References 2 |
Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009) |
Background References 3 |
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008) |
Background References 4 |
Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008) |
1st Image Caption |
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane). |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.