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OSTM1 Antibody

OSTM1 Antibody

ArtNr	PRS-59-814-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
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Shipping	blue ice or RT
By Research Area	Cancer, Cell Cycle, Cell Cycle, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Mouse
Immunogen	This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	37 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	OSTM1
Accession #	Q86WC4
Protein Gi #	51316434
Ncbi Gene Id #	28962
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	OSTM1
Ncbi Official Full Name	Osteopetrosis-associated transmembrane protein 1
Ncbi Organism	Homo sapiens
Swissprot #	Q86WC4
Background	This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.
Background References 1	Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Background References 2	Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)
Background References 3	Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
Background References 4	Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)
1st Image Caption	Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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