Hersteller |
ProSci
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Format |
Liquid |
Applikationen |
WB |
Menge |
400 ul |
Host |
Rabbit |
ArtNr |
PRS-58-985-400ul |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT |
Shipping |
blue ice or RT |
By Research Area |
Obesity, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Monkey |
Immunogen |
This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PPT1. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
34 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
PPT1 |
Accession # |
P50897 |
Protein Gi # |
1709747 |
Ncbi Gene Id # |
5538 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
PPT1 |
Ncbi Official Full Name |
Palmitoyl-protein thioesterase 1 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P50897 |
Background |
The protein encoded by this gene is a small glycoproteininvolved in the catabolism of lipid-modified proteins duringlysosomal degradation. The encoded enzyme removes thioester-linkedfatty acyl groups such as palmitate from cysteine residues. Defectsin this gene are a cause of infantile neuronal ceroidlipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis4 (CLN4). Two transcript variants encoding different isoforms havebeen found for this gene. |
Background References 1 |
Ohno, K., et al. Brain Dev. 32(7):524-530(2010) |
Background References 2 |
Simonati, A., et al. Pediatr. Neurol. 40(4):271-276(2009) |
Background References 3 |
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009) |
Background References 4 |
Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) : |
1st Image Caption |
Western blot analysis in A549 cell line lysates (35ug/lane). |
2nd Image Caption |
Western blot analysis of PPT1 using rabbit polyclonal PPT1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPT1 gene. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.