Vergleich

PPT1 Antibody

Hersteller ProSci
Kategorie
Typ Antibody Polyclonal
Specific against Human
Format Liquid
Applikationen WB
Menge 400 ul
Host Rabbit
ArtNr PRS-58-985-400ul
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Alias Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT
Shipping
blue ice or RT
By Research Area
Obesity, Signal Transduction
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen
This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PPT1.
Applications
For WB starting dilution is: 1:1000
Predicted Molecular Weight
34 kDa
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
PPT1
Accession #
P50897
Protein Gi #
1709747
Ncbi Gene Id #
5538
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
PPT1
Ncbi Official Full Name
Palmitoyl-protein thioesterase 1
Ncbi Organism
Homo sapiens
Swissprot #
P50897
Background
The protein encoded by this gene is a small glycoproteininvolved in the catabolism of lipid-modified proteins duringlysosomal degradation. The encoded enzyme removes thioester-linkedfatty acyl groups such as palmitate from cysteine residues. Defectsin this gene are a cause of infantile neuronal ceroidlipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis4 (CLN4). Two transcript variants encoding different isoforms havebeen found for this gene.
Background References 1
Ohno, K., et al. Brain Dev. 32(7):524-530(2010)
Background References 2
Simonati, A., et al. Pediatr. Neurol. 40(4):271-276(2009)
Background References 3
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Background References 4
Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) :
1st Image Caption
Western blot analysis in A549 cell line lysates (35ug/lane).
2nd Image Caption
Western blot analysis of PPT1 using rabbit polyclonal PPT1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPT1 gene.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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