LOXL2 Antibody

blue ice or RT

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat

For WB starting dilution is: 1:1000

This antibody is purified through a protein A column, followed by peptide affinity purification.

Rabbit Ig

Supplied in PBS with 0.09% (W/V) sodium azide.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

Q9Y4K0

4017

LOXL2

Homo sapiens

This gene encodes a member of the lysyl oxidase genefamily. The prototypic member of the family is essential to thebiogenesis of connective tissue, encoding an extracellularcopper-dependent amine oxidase that catalyses the first step in theformation of crosslinks in collagens and elastin. A highlyconserved amino acid sequence at the C-terminus end appears to besufficient for amine oxidase activity, suggesting that each familymember may retain this function. The N-terminus is poorly conservedand may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxisto each member of the family.

Ruckert, F., et al. IntColorectal Dis 25(3):303-311(2010)

Sano, M., et al. Int. J. Oncol. 36(2):321-330(2010)