Vergleich

CDH10 Antibody

ArtNr PRS-58-021-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, FC, IHC-P
Specific against Human
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cadherin-10, T2-cadherin, CDH10
Lieferbar
Shipping
blue ice or RT
By Research Area
Neuroscience, Signal Transduction
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen
This CDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human CDH10.
Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Predicted Molecular Weight
88 kDa
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
CDH10
Accession #
Q9Y6N8
Protein Gi #
116241276
Ncbi Gene Id #
1008
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
CDH10
Ncbi Official Full Name
Cadherin-10
Ncbi Organism
Homo sapiens
Swissprot #
Q9Y6N8
Background
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
Background References 1
Kools, P., FEBS Lett. 452 (3), 328-334 (1999)
1st Image Caption
Western blot analysis of CDH10 Antibody in NCI-H460 cell line lysates (35ug/lane)
2nd Image Caption
Formalin-fixed and paraffin-embedded human brain tissue reacted with CDH10 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
3rd Image Caption
Flow cytometric analysis of NCI-H460 cells using Cadherin 10 (CDH10) Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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