ArtNr |
PRS-57-962-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, p53-regulated ubiquitin-conjugating enzyme 1, UBE2D2, PUBC1, UBC4, UBC5B, UBC |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle |
Homology |
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus |
Immunogen |
This UBE2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the C-terminal region of human UBE2D2. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
17 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
UBE2D2 |
Accession # |
P62837 |
Protein Gi # |
51338685 |
Ncbi Gene Id # |
7322 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
UBE2D2 |
Ncbi Official Full Name |
Ubiquitin-conjugating enzyme E2 D2 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P62837 |
Background |
The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E2ubiquitin-conjugating enzyme family. This enzyme functions in theubiquitination of the tumor-suppressor protein p53, which isinduced by an E3 ubiquitin-protein ligase. Two alternativelyspliced transcript variants have been found for this gene and theyencode distinct isoforms. |
Background References 1 |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
Background References 2 |
Wu, K., et al. Mol. Cell 37(6):784-796(2010) |
Background References 3 |
Vina-Vilaseca, A., et al. J. Biol. Chem. 285(10):7645-7656(2010) |
Background References 4 |
Sakata, E., et al. Structure 18(1):138-147(2010) |
1st Image Caption |
Western blot analysis of lysate from Hela cell line, using UBE2D2 Antibody at 1:1000 at each lane. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.