Vergleich

OTU7B Antibody

ArtNr PRS-57-615-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC-P
Specific against Human
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1
Lieferbar
Shipping
blue ice or RT
By Research Area
Cell Cycle, Signal Transduction
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen
This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.
Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight
93 kDa
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
OTUD7B
Accession #
Q6GQQ9
Protein Gi #
51701318
Ncbi Gene Id #
56957
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
OTUD7B
Ncbi Official Full Name
OTU domain-containing protein 7B
Ncbi Organism
Homo sapiens
Swissprot #
Q6GQQ9
Background
OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
Background References 1
Bremm, A., et al. Nat. Struct. Mol. Biol. 17(8):939-947(2010)
Background References 2
Jin, Z., et al. Cell 137(4):721-735(2009)
Background References 3
Enesa, K., et al. J. Biol. Chem. 283(27):18582-18590(2008)
Background References 4
Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
1st Image Caption
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
2nd Image Caption
OTU7B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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