ArtNr |
PRS-57-215-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Toll-like receptor 7, TLR7 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Immunology, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Mouse |
Immunogen |
This TLR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-926 amino acids from the C-terminal region of human TLR7. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
121 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
TLR7 |
Accession # |
Q9NYK1 |
Protein Gi # |
20140876 |
Ncbi Gene Id # |
51284 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
TLR7 |
Ncbi Official Full Name |
Toll-like receptor 7 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9NYK1 |
Background |
The protein encoded by this gene is a member of theToll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs arehighly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associatedmolecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for thedevelopment of effective immunity. The various TLRs exhibitdifferent patterns of expression. This gene is predominantlyexpressed in lung, placenta, and spleen, and lies in closeproximity to another family member, TLR8, on chromosome X. |
Background References 1 |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
Background References 2 |
Manuse, M.J., et al. Virology 405(2):383-389(2010) |
Background References 3 |
Cros, J., et al. Immunity 33(3):375-386(2010) |
Background References 4 |
Shen, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15838-15843(2010) |
1st Image Caption |
Western blot analysis in HepG2 cell line lysates (35ug/lane). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.