Slc37A2 Antibody

blue ice or RT

Slc37A2 antibody was raised against a 15 amino acid synthetic peptide near the center of human Slc37A2.

The immunogen is located within amino acids 230 - 280 of Slc37A2.

Cat. No. 1406 - Mouse Spleen Tissue Lysate

Polyclonal

Unconjugated

1 mg/mL

Cat. No. 5647P – Slc37A2 Peptide

None

NP_938018

219855

SLC37A2

Homo sapiens

Slc37A2 Antibody: The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.

Kim JY, Tillison K, Zhou S, et al. The major facilitator superfamily member Slc37a2 is a novel macrophage-specific gene selectively expressed in obese white adipose tissue. Am. J. Physiol. Endocrinol. Metab.2007; 293:E110-20.

Immunohistochemistry of Slc37A2 in rat spleen tissue with Slc37A2 antibody at 5 μ g/mL.