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PKP2 Antibody

PKP2 Antibody

ArtNr	PRS-56-747-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Plakophilin-2, PKP2
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Shipping	blue ice or RT
By Research Area	Neuroscience, Signal Transduction
Immunogen	This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	97 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PKP2
Accession #	Q99959
Protein Gi #	296452867
Ncbi Gene Id #	5318
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PKP2
Ncbi Official Full Name	Plakophilin-2
Ncbi Organism	Homo sapiens
Swissprot #	Q99959
Background	This gene encodes a member of the arm-repeat (armadillo)and plakophilin gene families. Plakophilin proteins containnumerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments inthe cytoskeleton. This gene product may regulate the signalingactivity of beta-catenin. Two alternately spliced transcriptsencoding two protein isoforms have been identified. A processedpseudogene with high similarity to this locus has been mapped tochromosome 12p13.
Background References 1	Fressart, V., et al. Europace 12(6):861-868(2010)
Background References 2	Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010)
Background References 3	Christensen, A.H., et al. Cardiology 115(2):148-154(2010)
Background References 4	den Haan, A.D., et al. Circ Cardiovasc Genet 2(5):428-435(2009)
1st Image Caption	Western blot analysis in K562 cell line lysates (35ug/lane).
2nd Image Caption	PKP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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