ArtNr |
PRS-56-391-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle |
Immunogen |
This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
117 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
PITRM1 |
Accession # |
Q5JRX3 |
Protein Gi # |
485956568 |
Ncbi Gene Id # |
10531 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
PITRM1 |
Ncbi Official Full Name |
Presequence protease, mitochondrial |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q5JRX3 |
Background |
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. |
Background References 1 |
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) |
Background References 2 |
Pinho, C.M., et al. Neurosci. Lett. 469(2):204-208(2010) |
Background References 3 |
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) |
Background References 4 |
Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009) |
1st Image Caption |
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane). |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.