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MED6 Antibody

ArtNr PRS-56-225-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Mediator of RNA polymerase II transcription subunit 6, Activator-recruited cofactor 33 kDa component, ARC33, Mediator complex subunit 6, hMed6, Renal carcinoma antigen NY-REN-28, MED6, ARC33
Lieferbar
Shipping
blue ice or RT
Immunogen
This MED6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human MED6.
Applications
For WB starting dilution is: 1:1000
Predicted Molecular Weight
28 kDa
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
MED6
Accession #
O75586
Ncbi Gene Id #
10001
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
MED6
Ncbi Official Full Name
Mediator of RNA polymerase II transcription subunit 6
Ncbi Organism
Homo sapiens
Swissprot #
O75586
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Background References 1
Pavri, R., et al. Mol. Cell 18(1):83-96(2005)
Background References 2
Sato, S., et al. Mol. Cell 14(5):685-691(2004)
Background References 3
Yang, F., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2339-2344(2004)
Background References 4
Tomomori-Sato, C., et al. J. Biol. Chem. 279(7):5846-5851(2004)
1st Image Caption
Western blot analysis in HepG2 cell line lysates (35ug/lane).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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