ArtNr |
PRS-55-715-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC-P |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta, EIF2B4, EIF2BD |
Lieferbar |
|
Shipping |
blue ice or RT |
Homology |
Predicted species reactivity based on immunogen sequence: Bovine |
Immunogen |
This EIF2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 |
Predicted Molecular Weight |
58 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
EIF2B4 |
Accession # |
Q9UI10 |
Protein Gi # |
28381357 |
Ncbi Gene Id # |
8890 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
EIF2B4 |
Ncbi Official Full Name |
Translation initiation factor eIF-2B subunit delta |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9UI10 |
Background |
Eukaryotic initiation factor 2B (EIF2B), which isnecessary for protein synthesis, is a GTP exchange factor composedof five different subunits. The protein encoded by this gene is thefourth, or delta, subunit. Defects in this gene are a cause ofleukoencephalopathy with vanishing white matter (VWM) andovarioleukodystrophy. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq]. |
Background References 1 |
Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) : |
Background References 2 |
Wu, Y., et al. J. Hum. Genet. 54(2):74-77(2009) |
Background References 3 |
Horzinski, L., et al. PLoS ONE(12), E8318 (2009) : |
Background References 4 |
Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008) |
1st Image Caption |
Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF2B4 antibody detected the EIF2B4 protein (arrow). |
2nd Image Caption |
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the EIF2B4 antibody detected the EIF2B4 protein (arrow). |
3rd Image Caption |
E immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of E for immunohistochemistry. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.