ArtNr |
PRS-55-550-400ul |
Hersteller |
ProSci
|
Menge |
400 ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC-P |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon, PPM1L, PP2CE |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Bovine |
Immunogen |
This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 |
Predicted Molecular Weight |
41 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
PPM1L |
Accession # |
Q5SGD2 |
Protein Gi # |
74743437 |
Ncbi Gene Id # |
151742 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
PPM1L |
Ncbi Official Full Name |
Protein phosphatase 1L |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q5SGD2 |
Background |
PPM1L, or PP2CE, belongs to the PP2C group ofserine/threonine phosphatases, which are distinguished from otherphosphatases by their structure, absolute requirement for Mg(2+) orMn(2+), and insensitivity to okadaic acid. PP2Cs regulatestress-activated protein kinase (SAPK; see MIM 601158) signalingcascades that respond to extracellular stimuli (Jin et al., 2004[PubMed 15560375]). |
Background References 1 |
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : |
Background References 2 |
Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010) |
Background References 3 |
Trynka, G., et al. Gut 58(8):1078-1083(2009) |
Background References 4 |
Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008) |
1st Image Caption |
Western blot analysis in mouse heart tissue lysates (35ug/lane). |
2nd Image Caption |
PPM1L antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.